I'm a librarian who loves anime, manga, and reading a wide variety of genres.
Can kidney failure cause jaundice? All I can find is that it sometimes goes the other way around, with jaundice leading to kidney failure.
Anyway, I have some guesses as to what some of the book's final revelations will be, and there haven't even been any deaths yet. The things I know for sure: Lena and Robin are sisters, but they're both adopted and not sisters by blood. Robin needs a kidney, preferably one from a blood relative. Nurse Porter had an odd little conversation with Flynn, the English guy (the fact that he's English has been brought up many, many times), in which Flynn lied to her about both his mother and father living in Plymouth. Either that, or he lied to Shani about only his father living in Plymouth.
My guesses:(show spoiler)