I'm a librarian who loves anime, manga, and reading a wide variety of genres.
The massive amount of destruction and awfulness in this volume packs quite a punch. Even if people survive, they'll have to rebuild from scratch, because everything is gone. Unfortunately, again, there is no time to grieve, no time to stop and reflect on just how terrible all this is. Naruto and Pain are still fighting, and Naruto has gone super-super-powered.
Of all the deaths and near-deaths in this volume, the one that hit me the most was Kakashi. He has long been a favorite character of mine.
(Original review posted on A Library Girl's Familiar Diversions.)